
Santa Croce Vacations from $638
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Your Santa Croce Vacation
Our Santa Croce vacation packages are a fast and practical way to plan and reserve your next adventure. Uncover the true character of this unique neighborhood without the hassle of having to organize everything yourself. Some top nearby attractions to see during your trip to Santa Croce include Cathedral of Santa Maria del Fiore, Ponte Vecchio and Uffizi Gallery. Expedia can put your plans into action. Book your ultimate Santa Croce vacation now.
The Latest Santa Croce Vacation Packages

Aurum Firenze
Reviewed on Jan 3, 2026

Aurum Uffizi
Reviewed on Dec 15, 2025

Hotel degli Orafi
Reviewed on Jan 4, 2026

The Moon Boutique Hotel & Spa
Reviewed on Jan 2, 2026

Art Atelier
Reviewed on Jan 6, 2026
Where to stay in Santa Croce

Historic Centre of Florence
Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.
Santa Croce Hotel Deals

Aurum Uffizi
The room was fine and the staff friendly. However sometimes was not staffed in the afternoons and never after 1030.
Reviewed on Dec 19, 2025

LHP Hotel River & SPA
Very nice location. Staff are very attentive and helpful. Nice indoor outdoor bar. Excellent breakfast buffet.
Reviewed on Dec 12, 2025

Plaza Hotel Lucchesi
Excellent location. Staff was accommodative of our needs.
Reviewed on Dec 30, 2025
Discover the most popular places to visit in Santa Croce

Piazza Santa Croce
Italy’s most famous soccer game takes place here once a year, but the square is better known as a nighttime hangout of choice for young people.

Basilica of Santa Croce
Glorious tombs mark the resting place of Michelangelo, Galileo and many other Italian greats in the largest Franciscan church in the world.

National Central Library of Florence
Find out about the history of Florence when you take a trip to National Central Library of Florence. Discover the area's beautiful sunsets and stunning cathedral.
Things to do

Skip-the-Line Florence Duomo: Priority-Access Express Guided Tour

Florence: Timed Entry to Michelangelo's David + Audio App























