Santa Croce Vacations from $966
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Your Santa Croce Vacation
Our Santa Croce vacation packages are a fast and practical way to plan and reserve your next adventure. Uncover the true character of this unique neighborhood without the hassle of having to organize everything yourself. Some top nearby attractions to see during your trip to Santa Croce include Cathedral of Santa Maria del Fiore, Ponte Vecchio and Uffizi Gallery. Expedia can put your plans into action. Book your ultimate Santa Croce vacation now.
The Latest Santa Croce Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Hotel Duomo Firenze
Historic Centre of Florence
Price was $1,502, price is now $1,108 per person
$1,108
per person
Jan 18 - Jan 25
found 1 day ago
Roundtrip non-stop flight included
New York (JFK) to Florence (FLR)
9.2/10 Wonderful! (1,003 reviews)
Great location, very clean and beautiful views. Staff was very kind and helpful
Reviewed on Oct 28, 2026
Hotel La Scaletta Al Ponte Vecchio
Historic Centre of Florence
Price was $1,458, price is now $1,134 per person
$1,134
per person
Dec 8 - Dec 14
found 1 day ago
Roundtrip non-stop flight included
New York (JFK) to Florence (FLR)
9/10 Wonderful! (1,000 reviews)
We loved the rooftop bar. Spectacular. Staff was very helpful and friendly. WiFi was quite slow. Room was good. Toiletries were good. Great location.
Reviewed on Oct 29, 2026
Where to stay in Santa Croce
Find the best Santa Croce areas and neighborhoods for the activities you enjoy most. Learn more about Santa Croce
Historic Centre of Florence
10 out of top 10 points of interest in this area
Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.
Santa Croce Hotel Deals
Plaza Hotel Lucchesi
Lungarno Della Zecca Vecchia 38 Florence FI
Fully refundableReserve now, pay when you stay
$192 nightly
The price is $227 total per night from Nov 29 to Nov 30
$227 total
Nov 29 - Nov 30
Total with taxes and fees
9.4/10 Exceptional! (1,005 reviews)
"Lovely few days, shoutout to the very helpful rooftop bar staff."
Reviewed on Oct 28, 2026
FH55 Grand Hotel Mediterraneo
Lungarno del Tempio, 44 Florence FI
Fully refundableReserve now, pay when you stay
$108 nightly
The price is $134 total per night from Nov 1 to Nov 2
$134 total
Nov 1 - Nov 2
Total with taxes and fees
Hotel Balestri
Piazza Mentana 7 Florence FI
Fully refundableReserve now, pay when you stay
$166 nightly
The price is $198 total per night from Nov 30 to Dec 1
$198 total
Nov 30 - Dec 1
Total with taxes and fees
9.4/10 Exceptional! (1,001 reviews)
"Had a great room with access to a rooftop patio and a spectacular view"
Reviewed on Oct 21, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Santa Croce attractions
Things to do
Florence: Pasta & Tiramisu Cooking Class with Unlimited Wine
$20
per adult
94% of travellers recommend
City Sightseeing Florence Hop-on Hop-off Bus Tour
$26
per adult
74% of travellers recommend
Accademia timed-entry Ticket with App Guide
$44
per adult
90% of travellers recommend
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.